HMS Grafton was laid down in August 1934 as the fifth ship of nine G-class destroyers being built by British dockyards in the interwar years. Almost two years later, in March 1936, the ship was completed and joined the ranks of the Royal Navy.

HMS Grafton spent her early service days as part of the 1st Destroyer Flotilla operating in the Mediterranean. During the Spanish Civil War, HMS Grafton assisted in enforcing the non-intervention policy alongside warships of other nations.

During the outbreak of WW2 in September 1939, HMS Grafton was undergoing refits at Malta, being called back to British waters in the following October. In early 1940, Grafton underwent minor overhaul work before being assigned to escort convoys  headed for Norway.

At the same time, the war situation in France was looking desperate with the start of the Siege of Calais. Operation Dynamo, the allied effort of evacuating cut-off troops from Dunkirk, commenced shortly after. HMS Grafton answered the call and assisted with evacuating troops from the 27th, May 1940.

Two days later however, HMS Grafton spotted survivors of the previously sunk destroyer HMS Wakeful and stopped to commence rescue efforts. Stationary, Grafton presented herself as easy prey for any attacker. Soon enough, she found herself in the crosshairs of the German submarine U-62.

Although severely damaged by the torpedo attack, HMS Grafton stayed afloat long enough for her survivors to be rescued by the destroyer HMS Ivanhoe. Realizing the extent of her damage, the decision was made to scuttle HMS Grafton by gunfire from Ivanhoe. After the shelling, HMS Grafton quickly sank to the bottom, marking the end of her service life and contribution to WW2.